Article

The role of ATM in the regulation of interferon-gamma responses

2012-01-01

Abstract excerpt

Interferon (IFN)-γ is a key cytokine in the modulation of immune responses necessary for elimination of viral infections and some cancer cells. IFN-γ signals through the Janus kinase (JAK)/ signal transducers and activators of transcription (STAT) signalling pathways. Ataxia telangiectasia mutated (ATM) was identified by our group as a regulator of IFN-γ responses. Within DNA double-strand break (DSB) repair, ATM...

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Literature Corpus work: 2245d5ce-1e1a-5e6f-82c8-12267413c92f
DOI: 10.25560/10221

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