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Article

ATM: from gene to function.

Human molecular genetics - 1 Jan 1998

Rotman G, Shiloh Y

Abstract excerpt

The identification of ATM , the gene responsible for the pleiotropic recessive disease ataxia telangiectasia, has initiated extensive research to determine the functions of its multifaceted protein product. The ATM protein belongs to a family of protein kinases that share similarities at their C-terminal region with the catalytic domain of phosphatidylinositol 3-kinases. Studies with ataxia telangiectasia (A-T)...

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Identifiers

PMID: 9735376
DOI: 10.1093/hmg/7.10.1555

Genes

ATM

Provenance

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATM: from gene to function.PMID 9735376Read ↗

ATM: the product of the gene mutated in ataxia-telangiectasia.Semantic proximity Read ↗

Cancer risk and the ATM gene: a continuing debate.Semantic proximity Read ↗

Ataxia telangiectasia syndrome: moonlighting ATM.Semantic proximity Read ↗

ATM: genome stability, neuronal development, and cancer cross paths.Semantic proximity Read ↗

ATM kinase: Much more than a DNA damage responsive protein.Semantic proximity Read ↗

ATM and related protein kinases: safeguarding genome integrity.Semantic proximity Read ↗

The many substrates and functions of ATM.Semantic proximity Read ↗

What has the cloning of the ATM gene told us about ataxia telangiectasia?Semantic proximity Read ↗

The role of ATM in DNA damage responses and cancer.Semantic proximity Read ↗

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsSemantic proximity Read ↗

Ataxia‐telangiectasia, cancer and the pathobiology of the <i>ATM</i> geneSemantic proximity Read ↗

[Ataxia-telangiectasia: a review].Semantic proximity Read ↗

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