Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of ATM in DNA damage responses and cancer.

Oncogene - 24 Dec 1998

Canman C E, Lim D S

Abstract excerpt

Ataxia-telangiectasia (AT) is a complex, autosomal recessive disorder characterized by cerebellar ataxia, believed to result from progressive neurodegeneration, and telangiectasia, dilation of blood vessels within the eyes and parts of the facial region. AT patients suffer from recurrent infectio...

Topics

Animals
Ataxia Telangiectasia
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Proteins
DNA Damage
DNA-Binding Proteins
Genetic Predisposition to Disease
Humans
Neoplasms
Protein Serine-Threonine Kinases
Proteins
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Suppressor Proteins

Source

Identifiers

PMID: 9916992
DOI: 10.1038/sj.onc.1202577

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9916992-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of ATM in DNA damage responses and cancer.PMID 9916992Read ↗

ATM&A Key Determinant of Multiple Cellular Responses to IrradiationSemantic proximity Read ↗

DNA Damage Responses: Mechanisms and Roles in Human DiseaseSemantic proximity Read ↗

The ATM signaling network in development and diseaseSemantic proximity Read ↗

Ataxia telangiectasia syndrome: moonlighting ATM.Semantic proximity Read ↗

Multiple roles of ATM in monitoring and maintaining DNA integritySemantic proximity Read ↗

Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response.Semantic proximity Read ↗

ATM: the product of the gene mutated in ataxia-telangiectasia.Semantic proximity Read ↗

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsSemantic proximity Read ↗

The genetic defect in ataxia-telangiectasia.Semantic proximity Read ↗

ATM signaling and genomic stability in response to DNA damage.Semantic proximity Read ↗

A single ataxia telangiectasia gene with a product similar to PI-3 kinase.Semantic proximity Read ↗

ATM and related protein kinases: safeguarding genome integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.