Article
The role of ATM in DNA damage responses and cancer.
Oncogene - 24 Dec 1998
Canman C E, Lim D S
Abstract excerpt
Ataxia-telangiectasia (AT) is a complex, autosomal recessive disorder characterized by cerebellar ataxia, believed to result from progressive neurodegeneration, and telangiectasia, dilation of blood vessels within the eyes and parts of the facial region. AT patients suffer from recurrent infections caused by both cellular and humoral immune deficiencies and as a population, are significantly predisposed to...
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