Article

Transgenerational dynamics of rDNA copy number in <i>Drosophila</i> male germline stem cells

2017-10-07

Abstract excerpt

rDNA loci, composed of hundreds of tandemly duplicated arrays of rRNA genes, are known to be among the most unstable genetic elements due to their repetitive nature. rDNA instability underlies aging (replicative senescence) in yeast cells, however, its contribution to the aging of multicellular organisms is poorly understood. In this study, we investigate the dynamics of rDNA loci during aging in the Drosophila m...

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Literature Corpus work: 21e9c9c8-e68b-5afe-81a4-6e9592ff321e
DOI: 10.1101/199679

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