Article

The retrotransposon <i>R2</i> maintains <i>Drosophila</i> ribosomal DNA repeats

2021-07-12

Abstract excerpt

Ribosomal DNA (rDNA) loci contain the hundreds of tandemly repeated copies of ribosomal RNA genes needed to support cellular viability. This repetitiveness makes it highly susceptible to copy number (CN) loss, threatening multi-generational maintenance of rDNA. How this threat is counteracted to avoid extinction of the lineage has remained unclear. Here, we show that the rDNA-specific retrotransposon R2 is essent...

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Literature Corpus work: cad95203-cec6-5ba7-b3ee-3e5200c1d28a
DOI: 10.1101/2021.07.12.451825

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