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Multigenerational silencing dynamics control cell aging

3 Oct 2017

Abstract excerpt

Cellular aging plays an important role in many diseases, such as cancers, metabolic syndromes, and neurodegenerative disorders. There has been steady progress in identifying aging-related factors such as reactive oxygen species and genomic instability, yet an emerging challenge is to reconcile the contributions of these factors with the fact that genetically identical cells can age at significantly different...

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PMID: 29073021
DOI: 10.1073/pnas.1703379114

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