Article

The Y chromosome contributes to sex-specific aging in Drosophila

2017-06-26

Abstract excerpt

Heterochromatin suppresses repetitive DNA, and a loss of heterochromatin has been observed in aged cells of several species, including humans and Drosophila. Males often contain substantially more heterochromatic DNA than females, due to the presence of a large, repeat-rich Y chromosome, and male flies generally have shorter average life spans than females. Here we show that repetitive DNA becomes de-repressed mor...

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Literature Corpus work: ef5db595-f05c-502a-820e-b6684a6202b3
DOI: 10.1101/156042

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