Article

Prostate cancer risk stratification improved across multiple ancestries with new polygenic hazard score

2021-08-18

Abstract excerpt

<h4>Introduction</h4> Prostate cancer risk stratification using single-nucleotide polymorphisms (SNPs) demonstrates considerable promise in men of European, Asian, and African genetic ancestries, but there is still need for increased accuracy. We evaluated whether including additional SNPs in a prostate cancer polygenic hazard score (PHS) would improve associations with clinically significant prostate cancer in mu...

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Literature Corpus work: 21221c5b-eef1-5d8c-ad91-0d9ba74f43fe
DOI: 10.1101/2021.08.14.21261931

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