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Article

Organ-System Disease Identity Is Encoded in the Physical Grammar of Regulatory DNA

2026-03-23

Abstract excerpt

Regulatory DNA is not a passive sequence of binding sites. It is a structured physical medium governed by transformation rules—a grammar, in the formal sense—that encodes the organ-system identity of every gene it controls. Here we formalise this grammar using the framework of Pāṇini (c. 4th century BCE), whose classification of Sanskrit phonemes by their physical articulatory properties, and derivation of transfo...

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Literature Corpus work
210b7bb1-ad5f-5337-99be-2d20131c209a
DOI
10.20944/preprints202603.1746.v1
Open publication

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Organ-System Disease Identity Is Encoded in the Physical Grammar of Regulatory DNADOI 10.20944/preprints202603.1746.v1
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