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A Pāṇinian Grammar of the Human Genome: The Genomic Periodicity Index Encodes Functional Architecture and Evolutionary Innovation

2026-04-10

Abstract excerpt

We describe a three-level formal grammar of the human genome that emerges directly from DNA sequence without prior biological annotation. At the first level, the genome maintains a universal structural periodicity of approximately 400 base pairs — an alternation of repeat and unique sequence that we term the Genomic Periodicity Index (GPI). Local deviations from this periodicity, the GPI Deviation (GPID), identify...

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Literature Corpus work: 10d6db98-b55b-58d7-81bc-20e86434f26f
DOI: 10.20944/preprints202604.0713.v1

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