Article

Genetic differences between extreme and composite constitution types from whole exome sequences reveal actionable variations

2020-04-28

Abstract excerpt

Personalized medicine relies on successful identification of genome-wide variations that governs inter-individual differences in phenotypes and system level outcomes. In Ayurveda, assessment of composite constitution types “ Prakriti” forms the basis for risk stratification, predicting health and disease trajectories and personalized recommendations. Here, we report a novel method for identifying pleiotropic gene...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd3ec7ef-4ff7-51d9-b12a-e20255c4fd4d
DOI: 10.1101/2020.04.24.059006

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic differences between extreme and composite constitution types from whole exome sequences reveal actionable variationsDOI 10.1101/2020.04.24.059006Read

Whole Exome Sequencing in Healthy Individuals of Extreme Constitution Types Reveals Differential Disease Risk: A Novel Approach towards Predictive MedicineSemantic proximity Read

Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda.Semantic proximity Read

Epigenomics and Ayurgenomics: Molecular Analysis of Ayurvedic Prakriti in Personalized HealthcareSemantic proximity Read

Ayurgenomics for stratified medicine: TRISUTRA consortium initiative across ethnically and geographically diverse Indian populations.Semantic proximity Read

Classification of Ayurveda constitution types: A Deep Learning ApproachSemantic proximity Read

MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank.Semantic proximity Read

Comparative GWAS using global and Indian Reference Panels reveals non-coding drivers of COVID-19 severity and mortality.Semantic proximity Read

Pharmacogenomic landscape of Indian population using whole genomes.Semantic proximity Read

Phenome-wide association study of loci harboring <i>de novo</i> tandem repeat mutations in UK Biobank exomesSemantic proximity Read

A phenome-wide investigation of risk factors for severe COVID-19.Semantic proximity Read

Stratification of rheumatoid arthritis cohort using Ayurveda based deep phenotyping approach identifies novel genes in a GWASSemantic proximity Read

Long-read sequencing of 945 Han individuals identifies novel structural variants associated with phenotypic diversity and disease susceptibilitySemantic proximity Read