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Article

Long-range regulatory effects of Neandertal DNA in modern humans.

Genetics - 2 Mar 2023

Yermakovich Danat, Pankratov Vasili, Võsa Urmo, Yunusbayev Bayazit, Dannemann Michael

Abstract excerpt

The admixture between modern humans and Neandertals has resulted in ∼2% of the genomes of present-day non-Africans being composed of Neandertal DNA. Introgressed Neandertal DNA has been demonstrated to significantly affect the transcriptomic landscape in people today and via this molecular mechanism influence phenotype variation as well. However, little is known about how much of that regulatory impact is...

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Identifiers

PMID: 36560850
DOI: 10.1093/genetics/iyac188
PMCID: PMC9991505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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