Article

Spatial vascular/BTB remodeling and malignant-state plasticity in glioblastoma

2026-08-22

Abstract excerpt

<h4>Background</h4> Glioblastoma (GBM) contains spatially heterogeneous malignant and vascular states, but blood-tumor barrier (BTB) remodeling is often described as a binary functional phenotype. We asked whether anatomically distinct GBM compartments contain separable vascular programs that coexist with malignant-state plasticity. <h4>Methods</h4> We performed donor-aware cross-sectional analyses of 38 histopa...

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Literature Corpus work: 20ec32dc-aabc-580a-851f-63ff2fae84e4
DOI: 10.64898/2026.08.18.745357

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