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Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap

1 May 2025

Abstract excerpt

BACKGROUND: Glioblastoma (GB), particularly IDH-wild type, is the most aggressive brain malignancy with a dismal prognosis. Despite advances in molecular profiling, the complexity of its tumor microenvironment and spatial organization remains poorly understood. This study aimed to create a comprehensive single-cell and spatial atlas of GB to unravel its cellular heterogeneity, spatial architecture, and clinical...

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Ferroptosis and cancer prognosis
Glioma Diagnosis and Treatment
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40312969
DOI: 10.1093/neuonc/noaf113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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