Article

Cross-Modal Training Using Xenium Spatial Transcriptomics Enables DINO-DETR Based Detection of Vascular Niches in H&E Whole-Slide Images

2026-03-19

Abstract excerpt

<h4>Background</h4> Tumor vasculature is a key driver of glioma progression, yet routine quantification depends on subjective histopathologic assessment or resource-intensive ancillary immunohistochemistry. A scalable, objective method for vascular phenotyping from routine histology remains an unmet need. <h4>Methods</h4> We leveraged 10x Genomics Xenium spatial transcriptomics data from a glioblastoma specimen...

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Literature Corpus work: 1ec4c1bb-b589-5c24-980f-4a65fd9fb4f4
DOI: 10.64898/2026.03.17.712266

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