Article

3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma

2024-07-13

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma (GBM) is a lethal brain cancer with no effective treatment; understanding how GBM cells respond to tumor microenvironment remains challenging as conventional cell cultures lack proper cytoarchitecture while in vivo animal models present complexity all at once. Developing a culture system to bridge the gap is thus crucial. Here, we employed a multicellular approach using human glia...

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Literature Corpus work: 3016ebd8-a803-5875-be1b-4895d010d6d2
DOI: 10.1101/2024.07.09.601756

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