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Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosus

2025-04-30

Abstract excerpt

Systemic lupus erythematosus (SLE) presents with diverse and heterogenous cutaneous manifestations. However, the molecular and immunologic pathways driving specific cutaneous manifestations of SLE are poorly understood. Here, we leverage transcriptomics from a large well-phenotyped longitudinal cohort of SLE patients to map molecular pathways linked to ten distinct SLE-related rashes. Through whole blood and immun...

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Identifiers and source

Literature Corpus work
5d0389e8-087a-5d2c-8739-0f9a08595033
DOI
10.1101/2025.04.27.649460
Open publication

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Transcriptomic analysis reveals immune signatures associated with specific cutaneous manifestations of lupus in systemic lupus erythematosusDOI 10.1101/2025.04.27.649460
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