Article

Predicting human mRNA isoform levels from site-specific splicing kinetics <i>in silico</i>

2026-06-19

Abstract excerpt

Splicing of pre-mRNA can result in multiple possible mRNA isoforms per gene due to alternative splicing. The frequency at which individual isoforms occur depends on the intrinsic splicing kinetics of the pre-mRNA as well as intracellular chemical conditions. Computational modeling can potentially provide a platform to rapidly assess how variations in intracellular and environmental conditions, for example differen...

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Literature Corpus work: 1f7538b8-48a0-54a6-afbf-ff2e1f5f666f
DOI: 10.64898/2026.06.16.732643

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