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Analysis of alternative splicing uncovers a vastly expanded transcriptomic response to hypoxia in human vascular endothelial cells

2025-12-12

Abstract excerpt

<h4>ABSTRACT</h4> Hypoxia is a fundamental pathophysiological stimulus that plays important roles in multiple cardiopulmonary diseases. During hypoxic stress, cells adapt by undergoing widespread transcriptional reprogramming. The conventional approach to investigating this response has largely involved RNA-seq analysis which typically quantifies transcriptional output at the level of individual genes. However, a...

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Literature Corpus work
1841b851-1da9-5be2-b727-ff99ed90189c
DOI
10.64898/2025.12.09.693320
Open publication

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Analysis of alternative splicing uncovers a vastly expanded transcriptomic response to hypoxia in human vascular endothelial cellsDOI 10.64898/2025.12.09.693320
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