Article

Storm: Incorporating transient stochastic dynamics to infer the RNA velocity with metabolic labeling information

2023-06-23

Abstract excerpt

<h4> A bstract </h4> The time-resolved scRNA-seq (tscRNA-seq) provides the possibility to infer physically meaningful kinetic parameters, e.g., the transcription, splicing or RNA degradation rate constants with correct magnitudes, and RNA velocities by incorporating temporal information. Previous approaches utilizing the deterministic dynamics and steady-state assumption on gene expression states are insufficie...

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Literature Corpus work: 1397f4e1-f28e-5c85-8013-5d7625178f3c
DOI: 10.1101/2023.06.21.545990

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