Article

Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to graft-versus-leukemia

2020-04-10

Abstract excerpt

Resistance to the graft-versus-leukemia (GvL) effect remains the major barrier to successful allogeneic hematopoietic stem cell transplantation (allo-HSCT) for aggressive hematologic malignancies. The basis of GvL resistance for advanced lymphoid malignancies remains incompletely understood. We hypothesized that for patients with chronic lymphocytic leukemia (CLL) treated with allo-HSCT, leukemic cell-intrinsic fe...

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Literature Corpus work: 1e925628-5db5-53a3-8b97-7e1be7a81ffb
DOI: 10.1101/2020.04.09.033555

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