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Article

Genotype- and Age-Specific Relapse Dynamics in Childhood Acute Lymphoblastic Leukemia: A Longitudinal Mechanistic Study

2026-01-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Despite advances in front-line therapy for pediatric acute lymphoblastic leukemia (ALL), relapse remains a leading cause of treatment failure and mortality. Building on prior virtual investigations of TEL-AML1–associated leukemogenesis, this study evaluates post-remission relapse risk across pediatric ALL genotypes using mechanistic simulation. <bold>Methods<...

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Literature Corpus work
0f4110dd-2d90-5bec-94f0-9129489ca568
DOI
10.21203/rs.3.rs-8653812/v1
Open publication

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Genotype- and Age-Specific Relapse Dynamics in Childhood Acute Lymphoblastic Leukemia: A Longitudinal Mechanistic StudyDOI 10.21203/rs.3.rs-8653812/v1
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