Article
Coevolution of Leukemia and Host Immune Cells in Chronic Lymphocytic Leukemia.
Cold Spring Harbor perspectives in medicine - 3 Apr 2017
Purroy Noelia, Wu Catherine J
Abstract excerpt
Cumulative studies on the dissection of changes in driver genetic lesions in cancer across the course of the disease have provided powerful insights into the adaptive mechanisms of tumors in response to the selective pressures of therapy and environmental changes. In particular, the advent of next-generation-sequencing (NGS)-based technologies and its implementation for the large-scale comprehensive analyses of...
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