Article

Optimized Multiple Circular Sequence Alignment for Cyclic Peptide Motif Discovery

2026-08-01

Abstract excerpt

<h4> A bstract </h4> Head-to-tail (H2T) cyclized peptides are an increasingly important modality in drug discovery, combining high target affinity and selectivity with metabolic stability. Because their underlying chemistry is still that of a linear amino-acid chain, their linear sequence representation is the native input format of main-stream sequence generative models now driving de novo peptide design (Slou...

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Literature Corpus work: 1db5be2c-5d8a-5a29-9aae-024ea1eac7a8
DOI: 10.64898/2026.07.28.741376

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