Article

Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children

2019-03-28

Abstract excerpt

<h4>INTRODUCTION</h4> Cardiometabolic factors are implicated in the aetiology of Alzheimer’s disease and may lie on the pathways linking genetic variants to Alzheimer’s disease across the life course. We examined whether polygenic risk scores (PRS) were associated with cardiometabolic health indicators through childhood and adolescence. <h4>METHODS</h4> In 7,977 participants from the Avon Longitudinal Study of P...

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Literature Corpus work: 1d9a9e73-5390-522f-89f3-10b6a482df04
DOI: 10.1101/580548

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