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Article

Polygenic risk scores for the prediction of cardiometabolic disease.

European heart journal - 7 Jan 2023

O'Sullivan Jack W, Ashley Euan A, Elliott Perry M

Abstract excerpt

Cardiometabolic diseases contribute more to global morbidity and mortality than any other group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually small-effect genetic variants, represent an advance in our ability to predict the development and complications of cardiometabolic diseases. This article reviews the evidence supporting the use of PRS in seven common cardiometabolic...

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Identifiers

PMID: 36478054
DOI: 10.1093/eurheartj/ehac648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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