Article
A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study.
Behavior genetics - 1 May 2023
Gorelik Aaron J, Paul Sarah E, Karcher Nicole R, Johnson Emma C, Nagella Isha, Blaydon Lauren, Modi Hailey, Hansen Isabella S, Colbert Sarah M C, Baranger David A A, Norton Sara A, Spears Isaiah, Gordon Brian, Zhang Wei, Hill Patrick L, Oltmanns Thomas F, Bijsterbosch Janine D, Agrawal Arpana, Hatoum Alexander S, Bogdan Ryan
Abstract excerpt
Genetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However, whether these and other associations are present during childhood remains unclear. Using data from 5556 genomically-confirmed European ancestry youth who completed the baseline session of the ongoing the Adolescent Brain Cognitive DevelopmentSM Study (ABCD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.