Article

Endogenously expressed P2X5 includes a proportion of isoforms or transcript variants sensitive to extracellular ATP

2025-01-14

Abstract excerpt

The P2X receptor family comprises ATP-gated non-selective cation channels central to physiological processes across the nervous, immune, cardiovascular, respiratory, and reproductive systems. While P2X1, P2X2, P2X3, P2X4, and P2X7 are well-established as ATP-sensitive, P2X5 isoforms and transcript variants (TVs) have traditionally been considered ATP-insensitive, limiting their functional exploration. This study i...

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Literature Corpus work: 1d822011-8924-5c83-b9b8-cf38190eb1e5
DOI: 10.1101/2025.01.10.632374

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