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Article

Significance of P2X7 receptor variants to human health and disease.

Recent patents on DNA & gene sequences - 1 Apr 2011

Sluyter Ronald, Stokes Leanne

Abstract excerpt

The human P2X7 receptor is a trimeric ligand-gated cation channel coded by the P2XR7 gene located at chromosome position 12q24. P2X7 is expressed in a wide variety of normal and disease-associated cell types. Activation of this receptor by extracellular adenosine 5'-triphosphate results in numero...

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Identifiers

PMID: 21303345
DOI: 10.2174/187221511794839219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21303345-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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