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Article

P2X7 Variants in Oncogenesis.

Cells - 19 Jan 2021

Pegoraro Anna, De Marchi Elena, Adinolfi Elena

Abstract excerpt

The P2X7 receptor for extracellular ATP is a well-established mediator of tumoral development and progression both in solid cancers and hematological malignancies. The human P2X7 gene is highly polymorphic, and several splice variants of the receptor have been identified in time. P2X7 single-nucleotide polymorphisms (SNPs) have been broadly analyzed by studies relating them to pathologies as different as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33477845
DOI: 10.3390/cells10010189
PMCID: PMC7832898

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