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Article

Molecular biology of K(ATP) channels and implications for health and disease.

IUBMB life - 1 Oct 2009

Akrouh Alejandro, Halcomb S Eliza, Nichols Colin G, Sala-Rabanal Monica

Abstract excerpt

The ATP-sensitive potassium (K(ATP)) channel is expressed in most excitable tissues and plays a critical role in numerous physiological processes by coupling intracellular energetics to electrical activity. The channel is comprised of four Kir6.x subunits associated with four regulatory sulfonylurea receptors (SUR). Intracellular ATP acts on Kir6.x to inhibit channel activity, while MgADP stimulates channel...

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Identifiers

PMID: 19787700
DOI: 10.1002/iub.246
PMCID: PMC3241984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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