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Article

P2X7 Receptor in Hematological Malignancies

5 Mar 2021

Abstract excerpt

The P2X7 receptor is an ion channel gated by the nucleotide ATP, known for its role in immune responses and recently emerging as a critical onco-promoting factor. Lymphocytes, myeloid cells, and their precursors were among the first cells proved to express a functional P2X7 receptor; therefore, it is not surprising that lymphoproliferative and myeloproliferative diseases, also known as hematological malignancies,...

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PMID: 33763425
DOI: 10.3389/fcell.2021.645605

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