Article

Transcriptomic profiling of human γδ T cells reveals non-linear immune aging characterized by childhood transitions and relative stability in adulthood

2026-01-16

Abstract excerpt

γδ T cells are one of the first T cell subsets developing in early ontogeny and show various effector functions in immune homeostasis and response in the young and the old. However, their maturation trajectories from infancy to children, adults and elderly have not been systematically defined. Here, we generated a single-cell transcriptome atlas of 106,711 γδ T cells from 223 individuals spanning infancy to old ag...

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Literature Corpus work: 1cd79087-af6f-5863-a9b4-933a538c2db0
DOI: 10.64898/2026.01.15.699622

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