Article

Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity

2022-07-07

Abstract excerpt

Age-related changes in immune cell composition and functionality are associated with multimorbidity and mortality. However, many centenarians delay the onset of aging-related disease suggesting the presence of elite immunity that remains highly functional at extreme old age. To identify immune-specific patterns of aging and extreme human longevity, we analyzed novel single cell profiles from the peripheral blood m...

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Literature Corpus work: 55e264ab-490f-5a52-8f0a-ebf6fe864217
DOI: 10.1101/2022.07.06.498968

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Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevityDOI 10.1101/2022.07.06.498968Read

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