Article

Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence

2024-11-08

Abstract excerpt

Immunosenescence, or immune aging, is characterized by both changes in cell type abundance and a decline in cellular function, leading to increased susceptibility to immune-related diseases. Yet, the extent to which sex influences the dynamic composition of immune cells during immunosenescence remains unknown. Here, we use single-cell RNA sequencing in peripheral blood mononuclear cells from 982 donors to uncover...

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Literature Corpus work: 0f43a168-e95d-57b0-b0d8-a5b64ea379ab
DOI: 10.1101/2024.11.06.622096

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