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Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenarians

10 Jan 2023

Abstract excerpt

Peripheral blood immune cells have different molecular characteristics at different stages of the whole lifespan. Knowledge of circulating immune cell types and states from children to centenarians remains incomplete. We profiled peripheral blood mononuclear cells (PBMCs) of multiple age groups with single-cell RNA sequencing (scRNA-seq), involving the age ranges of 1-12 (G1), 20-30(G2), 30-60(G3), 60-80(G4), and...

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PMID: 36703979
DOI: 10.3389/fimmu.2022.1081889

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