Article
Phenotypic screen-based discovery of a small molecule that can increase adult neurogenesis and improve memory
2023-07-28
Abstract excerpt
Stem cells and neurogenesis persist in the postnatal and adult brain. Adult brain stem cells can be neuroprotective in disease and augment hippocampal-dependent cognitive function and thus are an important therapeutic target. Although many molecules have been discovered that regulate neurogenesis, few studies have attempted to amplify the process pharmacologically as a therapeutic goal. To address this gap, we use...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 1c66c3bd-7d35-5c30-a61c-2722503ca4b5
- DOI
- 10.1101/2023.07.27.550845