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Article

Phenotypic technologies in stem cell biology.

Cell chemical biology - 18 Mar 2021

Vandana J Jeya, Lacko Lauretta A, Chen Shuibing

Abstract excerpt

The high-throughput phenotypic screen (HTPS) has become an emerging technology to discover synthetic small molecules that regulate stem cell fates. Here, we review the application of HTPS to identify small molecules controlling stem cell renewal, reprogramming, differentiation, and lineage conversion. Moreover, we discuss the use of HTPS to discover small molecules/polymers mimicking the stem cell extracellular...

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Identifiers

PMID: 33651977
DOI: 10.1016/j.chembiol.2021.02.001
PMCID: PMC7979494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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