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Article

Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases.

Progress in brain research - 1 Jan 2004

Petrova Penka S, Raibekas Andrei, Pevsner Jonathan, Vigo Noel, Anafi Mordechai, Moore Mary K, Peaire Amy, Shridhar Viji, Smith David I, Kelly John, Durocher Yves, Commissiong John W

Abstract excerpt

Astrocytes and neurons in the central nervous system (CNS) interact functionally to mediate processes as diverse as neuroprotection, neurogenesis and synaptogenesis. Moreover, the interaction can be homotypic, implying that astrocyte-derived secreted molecules affect their adjacent neurons optimally vs remote neurons. Astrocytes produce neurotrophic and extracellular matrix molecules that affect neuronal growth,...

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PMID: 14699964
DOI: 10.1016/s0079-6123(03)46012-3

Genes

MANF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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