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Article

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.

Stem cells translational medicine - 1 May 2016

Thorne Natasha, Malik Nasir, Shah Sonia, Zhao Jean, Class Bradley, Aguisanda Francis, Southall Noel, Xia Menghang, McKew John C, Rao Mahendra, Zheng Wei

Abstract excerpt

UNLABELLED: Astrocytes are the predominant cell type in the nervous system and play a significant role in maintaining neuronal health and homeostasis. Recently, astrocyte dysfunction has been implicated in the pathogenesis of many neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. Astrocytes are thus an attractive new target for...

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Identifiers

PMID: 27034412
DOI: 10.5966/sctm.2015-0170
PMCID: PMC4835244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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