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Ketone bodies in cell physiology and cancer

8 Jan 2024

Abstract excerpt

Ketogenic diets (KDs), fasting, or prolonged physical activity elevate serum ketone bodies (KBs) levels, providing an alternative fuel source for the brain and other organs. However, KBs play pleiotropic roles that go beyond their role in energy production. KBs can act as signaling metabolites, influence gene expression, proteins' posttranslational modifications (PTMs), inflammation, and oxidative stress. Here,...

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PMID: 38189128
DOI: 10.1152/ajpcell.00441.2023

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