Article

A ketogenic diet reduces age-induced chronic neuroinflammation in mice

2023-12-04

Abstract excerpt

Beta-hydroxybutyrate (BHB) is a ketone body synthesized during fasting or strenuous exercise. Our previous study demonstrated that a cyclic ketogenic diet (KD), which induces BHB levels similar to fasting every other week, reduces midlife mortality and improves memory in aging mice. BHB actively regulates gene expression and inflammatory activation through non-energetic signaling pathways. Neither of these activit...

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Literature Corpus work: 57a32a81-0867-5ff0-a931-fa0128d94fd3
DOI: 10.1101/2023.12.01.569598

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