Article

CRISPR delivery particles for developing therapeutic strategies in metabolic disease

2018-06-21

Abstract excerpt

<h4>ABSTRACT</h4> RNA-guided engineered nucleases derived from a prokaryotic adaptive immune system known as CRISPR-Cas represent a promising platform for gene deletion and editing. As a therapeutic approach, direct delivery of Cas9 protein and guide RNA could circumvent the safety problems associated with plasmid delivery and therefore represents an attractive tool for genome engineering. Gene deletion or editin...

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Literature Corpus work: 1bdfa9ec-64e1-55a6-a122-20958e346205
DOI: 10.1101/352799

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