Article
A review: Possible optimization of Cas9-sgRNA nuclease delivery via ingested lipid nanoparticles bioencapsulated within plant cell-based enfolding
2019-06-07
Abstract excerpt
The possibility of gene editing to correct disorders is one of the most impactful therapeutic agents, currently. CRISPR Cas9-sgRNA nucleases can be used to cleave and to delete harmful or pathogenic DNA sequences, which cause genetic disorders. Cas9 nuclease with palindromic repeats can cut and delete a single point mutation or multiple DNA target site sequences. The Cas9, attached to a sgRNA or a guiding RNA, fin...
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Identifiers and source
- Literature Corpus work
- fabe3105-dceb-57de-aa7e-a98f642e96d0
- DOI
- 10.7287/peerj.preprints.27709v2
