Article

Targeted delivery of RNA-based therapeutics enables functional analysis of macrophage subpopulations

2025-03-14

Abstract excerpt

Macrophages infiltrate all human tissues where they play key roles in innate immunity, homeostasis, and tissue function. However, extensive clinical and experimental evidence indicates that macrophages also contribute significantly to the progression of several diseases such as cancer, cardiometabolic disorders, and inflammatory and neurodegenerative conditions. Advances in single-cell omics have revealed diverse...

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Literature Corpus work: dd5ac476-fe54-50b7-93db-0d26fdd196a6
DOI: 10.1101/2025.03.12.642907

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