Article
Conditional lethality profiling reveals anticancer mechanisms of action and drug-nutrient interactions
2023-06-06
Abstract excerpt
<h4>SUMMARY</h4> Chemical screening studies have identified drug sensitivities across hundreds of cancer cell lines but most putative therapeutics fail to translate. Discovery and development of drug candidates in models that more accurately reflect nutrient availability in human biofluids may help in addressing this major challenge. Here we performed high-throughput screens in conventional versus Human Plasma-Li...
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Identifiers and source
- Literature Corpus work
- 1b454ca7-58ec-52b0-b622-e2fd9a6a42f5
- DOI
- 10.1101/2023.06.04.543621