Article

IL-11 disrupts alveolar epithelial progenitor function

2022-11-12

Abstract excerpt

IL-11 is linked to the pathogenesis of idiopathic pulmonary fibrosis (IPF), since IL-11 induces myofibroblast differentiation and stimulates their excessive collagen deposition in the lung. The alveolar architecture is disrupted in IPF, yet the effect of IL-11 on dysregulated alveolar repair associated with IPF remains to be elucidated. We hypothesized that epithelial-fibroblast communication associated with lung...

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Literature Corpus work: 1b0b980a-72b0-5fcb-8eb9-932a31fcf4de
DOI: 10.1101/2022.11.11.516088

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