Article

Recapitulating idiopathic pulmonary fibrosis related alveolar epithelial dysfunction in an iPSC-derived air-liquid interface model

2019-11-04

Abstract excerpt

<h4>ABSTRACT</h4> An abnormal emergence of airway epithelial-like cells within the alveolar compartments of the lung, herein termed bronchiolization, is a process often observed in patients suffering from idiopathic pulmonary fibrosis (IPF), a fatal disease characterized by progressive fibrotic lung remodeling. However, the origin of this dysfunctional epithelium remains unknown. In this study, we aimed to invest...

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Literature Corpus work: 41e9a072-d41c-581d-ac2c-af591934170f
DOI: 10.1101/830109

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