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Alveolar wars: The rise of in vitro models to understand human lung alveolar maintenance, regeneration, and disease

9 Apr 2020

Abstract excerpt

Abstract Diseases such as idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and bronchopulmonary dysplasia injure the gas-exchanging alveoli of the human lung. Animal studies have indicated that dysregulation of alveolar cells, including alveolar type II stem/progenitor cells, is implicated in disease pathogenesis. Due to mouse-human differences, there has been a desperate need to develop...

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PMID: 32272001
DOI: 10.1002/sctm.19-0433

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