Article

Accurate simultaneous sequencing of genetic and epigenetic bases in DNA

2022-07-09

Abstract excerpt

DNA comprises molecular information stored via genetic bases (G, C, T, A) and also epigenetic bases, principally 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). Both genetic and epigenetic information are vital to our understanding of biology and disease states. Most DNA sequencing approaches address either genetics or epigenetics and thus capture incomplete information. Methods widely used to detect ep...

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Literature Corpus work: 1abe8aaf-7608-595f-a31f-b589381fbd69
DOI: 10.1101/2022.07.08.499285

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